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heritEWAS (version 0.2.0)

Identify Heritable Methylation Marks

Description

A novel statistical method based on expectation maximisation (EM) algorithm and genetic segregation analysis to identify heritable DNA methylation marks. Details about the method can be found in Joo et al. (2018) .

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Version

Install

install.packages('heritEWAS')

Monthly Downloads

14

Version

0.2.0

License

GPL-3

Maintainer

Kevin Wong

Last Published

June 4th, 2020

Functions in heritEWAS (0.2.0)

heritEWAS-package

heritEWAS: Identify heritable DNA methylation marks from families
ML_estimates

Compute maximum likelihood estimates and \(\Delta\)l
ped

Simulated data on 20 families.
carrier_probabilities

Calculate carrier probabilities for the most heritable methylation sites
M_values

M-values for 1000 DNA methylation sites
genotype_combinations

Calculate genotype probabilities