abraham2024

Abraham2024

<p>Abraham et al. 2024
Abraham et al. (2024) (tools:::Rd_expr_doi("10.1016/j.envint.2024.109047")) determined the 
half-lives of 15 per- and 
polyfluoroalkyl substances in a single male volunteer.</p>

data

High throughput toxicokinetics ("HTTK") is the
combination of 1) chemical-specific in vitro measurements or in
silico predictions and 2) generic mathematical models, to
predict absorption, distribution, metabolism, and excretion by the
body. HTTK methods have been described by Pearce et al. (2017)
(<doi:10.18637/jss.v079.i04>) and Breen et al. (2021) (<doi:10.1080/17425255.2021.1935867>).
Here we provide examples (vignettes) applying HTTK to solve various
problems in bioinformatics, toxicology, and exposure science.
In accordance with Davidson-Fritz et al. (2025) (<doi:10.1371/journal.pone.0321321>),
whenever a new HTTK model is developed, the code to generate the
figures evaluating that model is added as a new vignettte.

John Wambaugh

httkexamples

High-Throughput Toxicokinetics Examples

Robert Pearce

Caroline Ring

Greg Honda

Matt Linakis

Dustin Kapraun

Kimberly Truong

Meredith Scherer

Annabel Meade

Celia Schacht

Elaina Kenyon

abraham2024 function

Format

Abraham et al. 2024
Abraham et al. (2024) (tools:::Rd_expr_doi("10.1016/j.envint.2024.109047")) determined the 
half-lives of 15 per- and 
polyfluoroalkyl substances in a single male volunteer. — abraham2024

Abraham et al. 2024
Abraham et al. (2024) (tools:::Rd_expr_doi("10.1016/j.envint.2024.109047")) determined the 
half-lives of 15 per- and 
polyfluoroalkyl substances in a single male volunteer.

abraham2024: Abraham et al. 2024 Abraham et al. (2024) (tools:::Rd_expr_doi("10.1016/j.envint.2024.109047")) determined the half-lives of 15 per- and polyfluoroalkyl substances in a single male volunteer.

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