huh2011

Huh2011

<p>Huh et al. 2011
Huh et al. (2011) (tools:::Rd_expr_doi("10.3109/00498254.2011.598582")) provided interspecies
allometric scaling parameters for whole body clearance for a a variety of 
pharmaceuticals.</p>

data

High throughput toxicokinetics ("HTTK") is the
combination of 1) chemical-specific in vitro measurements or in
silico predictions and 2) generic mathematical models, to
predict absorption, distribution, metabolism, and excretion by the
body. HTTK methods have been described by Pearce et al. (2017)
(<doi:10.18637/jss.v079.i04>) and Breen et al. (2021) (<doi:10.1080/17425255.2021.1935867>).
Here we provide examples (vignettes) applying HTTK to solve various
problems in bioinformatics, toxicology, and exposure science.
In accordance with Davidson-Fritz et al. (2025) (<doi:10.1371/journal.pone.0321321>),
whenever a new HTTK model is developed, the code to generate the
figures evaluating that model is added as a new vignettte.

John Wambaugh

httkexamples

High-Throughput Toxicokinetics Examples

Robert Pearce

Caroline Ring

Greg Honda

Matt Linakis

Dustin Kapraun

Kimberly Truong

Meredith Scherer

Annabel Meade

Celia Schacht

Elaina Kenyon

huh2011 function

Format

Huh et al. 2011
Huh et al. (2011) (tools:::Rd_expr_doi("10.3109/00498254.2011.598582")) provided interspecies
allometric scaling parameters for whole body clearance for a a variety of 
pharmaceuticals. — huh2011

Huh et al. 2011
Huh et al. (2011) (tools:::Rd_expr_doi("10.3109/00498254.2011.598582")) provided interspecies
allometric scaling parameters for whole body clearance for a a variety of 
pharmaceuticals.

huh2011: Huh et al. 2011 Huh et al. (2011) (tools:::Rd_expr_doi("10.3109/00498254.2011.598582")) provided interspecies allometric scaling parameters for whole body clearance for a a variety of pharmaceuticals.

Description

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References