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hwde (version 0.65)

hwexact: Exact test of HWE

Description

This function implements an exact SNP test of Hardy-Weinberg equilibrium. It is a wrapper for snphwe

Usage

hwexact(obs.hom1, obs.hets, obs.hom2, data, loci, observed)

Arguments

obs.hom1
Observed number of individuals homozygous for the common allele.
obs.hets
Observed number of heterozygous individuals.
obs.hom2
Observed number of individuals homozygous for the rare allele.
data
If not NULL, specifies a data frame holding the data.
loci
If data is not NULL, column that holds some combination of symbols of the form AA, Aa and aa.
observed
Column that holds the frequencies, if data is not NULL.

Value

  • The exact p-value testing departure from Hardy-Weinberg Equilibrium, conditional on the observed relative numbers of alleles of the two types

References

Wigginton, J.E.; Cutler, D.J. & Abecasis, G.R.; A Note on exact tests of Hardy-Weinberg equilibrium; American Journal of Human Genetics, 2005, 76, 887-93

Examples

Run this code
hwexact(68, 28, 4)

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