idarps (version 0.0.5)

codex: codex

Description

This dataset is based on an observational study conducted at Geneva University Hospitals to assess the impact of weight on the pharmacokinetics of dexamethasone in normal-weight versus obese patients hospitalized for COVID-19.

Usage

codex

Format

id

ID of the patient

gender

Gender (0 for men and 1 for women)

age

Age

bmi

Body mass index

weight

Weight in kg

number_doses

Number of doses of the dexamethasone (DEX) drug

tmax

The time it takes for the drug to reach the maximum concentration (i.e. Cmax) after its administration in hours (h)

cmax

The maximum concentration that achieves in the blood after the drug has been administered (ng/m)

t1_2

t1_2 is the time required to decrease the drug concentration within the body by one-half during elimination in hours (h)

auc

The integral (from 0 to 8 hours) of a curve that describes the variation of a drug concentration in the blood as a function of time it takes for a drug to reach the maximum concentration (Cmax) after administration of a drug (ng.h/m)

length_hospital

Number of days the patient were hospitalized

length_intermed

Number of days the patient were hospitalized at the intermediate and intensive care unit

crp

crp

comor_e

Presence of cormobidity type e

comor_p

Presence of cormobidity type p

comor_v

Presence of cormobidity type v

comor_c

Presence of cormobidity type c

comor_r

Presence of cormobidity type r

obese

Indicator variable based on whether the subject is obese (i.e. with BMI > 30), 0 for no and 1 for yes.