gene_chromosome_data

A dataset containing the chromosome information of the gene expression and methylation array data to be analysed.

datasets

A joint mixture model has been developed by Majumdar et al. (2025) <doi:10.48550/arXiv.2412.17511> that integrates information from gene expression data and methylation data at the modelling stage to capture their inherent dependency structure, enabling simultaneous identification of differentially methylated cytosine-guanine dinucleotide (CpG) sites and differentially expressed genes. The model leverages a joint likelihood function that accounts for the nested structure in the data, with parameter estimation performed using an expectation-maximisation algorithm.

Koyel Majumdar

idiffomix

Integrated Differential Analysis of Multi Omics Data using a
Joint Mixture Model

Isobel Claire Gorley

Thomas Brendan Murphy

Florence Jaffrezic

Andrea Rau

gene_chromosome_data function

A data frame with 20 rows and 2 columns.<ul>
<li>CHR: The chromosome containing the gene.</li>
<li>Gene: The gene located on the chromosome.</li>
</ul>

Format

Data containing chromosome information and the genes located on them. — gene_chromosome_data

Data containing chromosome information and the genes located on them.

gene_chromosome_data: Data containing chromosome information and the genes located on them.

Description

Usage

Arguments

Format

Details

See Also