intensity_PXD000052

This dataset has been collected during a study designed to perform the proteomic analysis of the SLP76 interactome in resting and activated primary mast cells. Four SLP76 replicates (with two analytical replicates each) have been affinity-purified from both resting and activated primary mast cells. The dataset within this package contains proteins intensity processed using MaxQuant. More information can be found on ProteomeExchange public repository (http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD000052) or in the original paper (see reference).

datasets

The package contains a collection of functions for left-censored missing data imputation. Left-censoring is a special case of missing not at random (MNAR)  mechanism that generates non-responses in proteomics experiments. The package also contains functions to artificially generate peptide/protein expression data (log-transformed) as random draws from a multivariate Gaussian distribution as well as a function to generate missing data (both randomly and non-randomly). For comparison reasons, the package also contains several wrapper functions for the imputation of non-responses that are missing at random. 

Cosmin Lazar

imputeLCMD

A collection of methods for left-censored missing data
        imputation

intensity_PXD000052 function

Original MaxQuant data: http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD000052

intensity_PXD000052: Dataset PXD000052 from ProteomeXchange.

Description

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source

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Examples