smeltz2023.uc: smeltz2023plasma;textualinvitroTKdata Ultracentrifugation Level-2 Data Set

Description

Mass Spectrometry measurements of plasma protein binding measured by ultracentrifugation (UC) for per- and poly-fluorinated alkyl substance (PFAS) samples from experiments led by Dr.s Marci Smeltz and Barbara Wetmore.

Usage

smeltz2023.uc

Arguments

Format

A level-2 data.frame with 10,133 rows and 23 variables:

Lab.Sample.Name: Sample description used in the laboratory
Date: Date sample was acquired
Compound.Name: Compound name
DTXSID: DSSTox Substance Identifier (CompTox Chemicals Dashboard)
Lab.Compound.Name: Compound as described in the laboratory
Sample.Type: Type of UC sample
Dilution.Factor: Number of times the sample was diluted
Calibration: Identifier for mass spectrometry calibration -- usually the date
Standard.Conc: Concentration of analytic standard (for calibration curve) (uM)
UC.Assay.T1.Conc: Intended concentration of chemical in T1 sample (uM)
ISTD.Name: Name of compound used as internal standard (ISTD)
ISTD.Conc: Concentration of ISTD (uM)
ISTD.Area: Peak area of internal standard (pixels)
Series: Identifier for replicate series of UC measurements
Area: Peak area of analyte (target compound)
Analysis.Method: General description of chemical analysis method
Analysis.Instrument: Instrument(s) used for chemical analysis
Analysis.Parameters: Parameters for identifying analyte peak (for example, retention time)
Note: Any laboratory notes about sample
Level0.File: Name of data file from laboratory that was used to compile level-0 data.frame
Level0.Sheet: Name of "sheet" (for Excel workbooks) from which the laboratory data were read
Response: Response factor (calculated from analyte and ISTD peaks)
Verified: If "Y", then sample is included in the analysis. (Any other value causes the data to be ignored.)

References

howard2010plasmainvitroTKdata

smeltz2023plasmainvitroTKdata