Heaviside

Evaluate the Heaviside function with <code>threshold</code> indicating the discontinuity.
If elements in <code>x</code> are greater than or equal to <code>threshold</code>, returns 1.
Otherwise, returns 0.

A set of tools for processing and analyzing in vitro toxicokinetic
measurements in a standardized and reproducible pipeline. The package
was developed to perform frequentist and Bayesian estimation on a
variety of in vitro toxicokinetic measurements including -- but not
limited to -- chemical fraction unbound in the presence of plasma
(f_up), intrinsic hepatic clearance (Clint,
uL/min/million hepatocytes), and membrane permeability for
oral absorption (Caco2). The methods provided
by the package were described in Wambaugh et al. (2019) <doi:10.1093/toxsci/kfz205>.

Caroline Ring

invitroTKstats

In Vitro Toxicokinetic Data Processing and Analysis Pipeline

John Wambaugh

Sarah E. Davidson-Fritz

Lindsay Knupp

Barbara A. Wetmore

Zhao Zhihui

Chantel Nicolas

Anna Kreutz

U.S. Federal Government 

Heaviside function

<dl><dt>x</dt>
<dd>(Numeric) A numeric vector.</dd>
<dt>threshold</dt>
<dd>(Numeric) A threshold value used to compare to elements in <code>x</code>. (Defaults to 0.)</dd></dl>

Arguments

Heaviside — Heaviside

<dl>

<dt>x</dt>
<dd>(Numeric) A numeric vector.</dd>


<dt>threshold</dt>
<dd>(Numeric) A threshold value used to compare to elements in <code>x</code>. (Defaults to 0.)</dd>

</dl>

Heaviside: Heaviside

Description

Usage

Value

Arguments