initfunction_clint

Sets the initial values of arguments required for JAGS such as assumed initial probability
distributions. The list is used as an argument to JAGS during level-4 processing.

A set of tools for processing and analyzing in vitro toxicokinetic
measurements in a standardized and reproducible pipeline. The package
was developed to perform frequentist and Bayesian estimation on a
variety of in vitro toxicokinetic measurements including -- but not
limited to -- chemical fraction unbound in the presence of plasma
(f_up), intrinsic hepatic clearance (Clint,
uL/min/million hepatocytes), and membrane permeability for
oral absorption (Caco2). The methods provided
by the package were described in Wambaugh et al. (2019) <doi:10.1093/toxsci/kfz205>.

Caroline Ring

invitroTKstats

In Vitro Toxicokinetic Data Processing and Analysis Pipeline

John Wambaugh

Sarah E. Davidson-Fritz

Lindsay Knupp

Barbara A. Wetmore

Zhao Zhihui

Chantel Nicolas

Anna Kreutz

U.S. Federal Government 

initfunction_clint function

<dl><dt>mydata</dt>
<dd>(List) Output of <code>build_mydata_clint</code>.</dd>
<dt>seed</dt>
<dd>(Numeric) Random Number Generator (RNG) seed to use for reproducibility.</dd></dl>

Arguments

Set Initial Values for Intrinsic Hepatic Clearance (Clint) Bayesian Model — initfunction_clint

<dl>

<dt>mydata</dt>
<dd>(List) Output of <code>build_mydata_clint</code>.</dd>


<dt>seed</dt>
<dd>(Numeric) Random Number Generator (RNG) seed to use for reproducibility.</dd>

</dl>

Set Initial Values for Intrinsic Hepatic Clearance (Clint) Bayesian Model

initfunction_clint: Set Initial Values for Intrinsic Hepatic Clearance (Clint) Bayesian Model

Description

Usage

Value

Arguments