scale_conc

Takes in vivo toxicokinetic concentration-time data and fits
parameters of 1-compartment and 2-compartment models for each
chemical. These methods are described in detail in "Informatics for Toxicokinetics" (2025).

John Wambaugh

invivoPKfit

Fits Toxicokinetic Models to In Vivo PK Data Sets

Caroline Ring

Gilberto Padilla Mercado

Chris Cook

scale_conc function

<dl><dt>dose_norm</dt>
<dd>Logical: Whether to normalize observed concentrations (and
observed concentration standard deviations and limits of quantification) by
dividing them by the corresponding dose. Default `FALSE`.</dd>
<dt>log10_trans</dt>
<dd>Logical: Whether to apply a `log10()` transformation to
observed concentrations (and limits of quantification), after any dose
normalization is applied. Default `FALSE`.</dd>
<dt>...</dt>
<dd>Other arguments (not currently used)</dd></dl>

Arguments

Author

Scale concentrations — scale_conc

<dl>

<dt>dose_norm</dt>
<dd>Logical: Whether to normalize observed concentrations (and
observed concentration standard deviations and limits of quantification) by
dividing them by the corresponding dose. Default `FALSE`.</dd>


<dt>log10_trans</dt>
<dd>Logical: Whether to apply a `log10()` transformation to
observed concentrations (and limits of quantification), after any dose
normalization is applied. Default `FALSE`.</dd>


<dt>...</dt>
<dd>Other arguments (not currently used)</dd>

</dl>

Scale concentrations

scale_conc: Scale concentrations

Description

Usage

Value

Arguments

Author