settings_preprocess: Data preprocessing settings

Description

Data preprocessing settings

Usage

settings_preprocess(
  routes_keep = c("oral", "iv"),
  media_keep = c("blood", "plasma", "excreta"),
  ratio_conc_dose = 1,
  impute_loq = TRUE,
  calc_loq_factor = 0.9,
  impute_sd = TRUE,
  keep_data_original = TRUE,
  suppress.messages = FALSE,
  ...
)

Value

An object of class `pk_settings_preprocess`. This is a named list of the arguments provided to this function and their values.

Arguments

routes_keep: Character: A list of routes to keep. Data will be filtered so that the harmonized variable `Route` includes only values in `routes_keep`. Default is `c("oral", "iv")`.
media_keep: Character: A list of media to keep. Data will be filtered so that the harmonized variable name `Media` includes only values in `media_keep`. Default is `c("blood", "plasma")`.
ratio_conc_dose: Numeric: The ratio of mass units of observed concentrations to mass units of applied doses. Default 1, to indicate the same mass units are used for both.
impute_loq: TRUE or FALSE: Whether to impute missing LOQ values.
calc_loq_factor: A numeric factor used for imputing missing LOQ. Within each group defined in `loq_group`, any missing LOQ values will be imputed as the minimum detected Value in the group, multiplied by `calc_loq_factor`. Default 0.9.
impute_sd: TRUE or FALSE: Whether to impute missing SD values.
keep_data_original: TRUE or FALSE: Whether to keep original data after pre-processing.
suppress.messages: TRUE or FALSE: Whether to suppress verbose messages. Default FALSE.
...: Any additional arguments. Currently ignored.

Author

Caroline Ring