invivoPKfit (version 2.0.2)

tkstats_httk_gas_pbtk: TK stats for gas_pbtk model fit with inivivoPKfit

Description

TK stats for gas_pbtk model fit with inivivoPKfit

Usage

tkstats_httk_gas_pbtk(
  pars,
  route,
  medium,
  dose,
  time_unit,
  conc_unit,
  vol_unit,
  this_chem,
  this_species,
  ...
)

Value

A `data.frame` with two variables: - `param_name` = `c("CLtot", "CLtot/Fgutabs", "Css_1mgkgday", "halflife", "Cmax", "AUC_infinity")` - `param_value` = The corresponding values for each statistic (which may be NA if that statistic could not be computed).

Arguments

pars

A named numeric vector of model parameters (e.g. from [coef.pk()]).

route

Character: The route for which to compute TK stats. Currently only "oral" and "iv" are supported.

medium

Character: the media (tissue) for which to compute TK stats. Currently only "blood" and "plasma" are supported.

dose

Numeric: A dose for which to calculate TK stats.

time_unit

Character: the units of time.

conc_unit

Character: The units of concentration.

vol_unit

Character: The units of dose.

this_chem

Character: The DTXSID of a chemical.

this_species

Character: The species of a subject.

...

Additional arguments not currently in use.

Author

Gilberto Padilla Mercado