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ipdmeta (version 2.4)

Tools for subgroup analyses with multiple trial data using aggregate statistics

Description

This package provides functions to estimate an IPD linear mixed effects model for a continuous outcome and any categorical covariate from study summary statistics. There are also functions for estimating the power of a treatment-covariate interaction test in an individual patient data meta-analysis from aggregate data.

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Version

Install

install.packages('ipdmeta')

Monthly Downloads

22

Version

2.4

License

GPL-2

Maintainer

S A Kovalchik

Last Published

September 4th, 2012

Functions in ipdmeta (2.4)

ipdmeta

Tools for subgroup analyses with multiple trial data using aggregate statistics
ipd.sep

IPD meta-analysis Subgroup Effect Power Estimator
poynard

Meta-analysis data set for Poynard et al. review of beta-adrenergic-antagonist drugs
converged

Extract the convergence status for an ipdlme object
ranef

Extract the study random effects for an ipdlme object
VcovRanef

Extract the variance-covariance matrix for study random effect estimates for an ipdlme object
fixef

Extract the population (fixed effect) estimates for an ipdlme object
ipdlme

IPD Linear Mixed-Effects Models from Aggregate Data
plot

Forest plot of study random effects for an ipdlme object
regress_chol

Aggregated data set of REGRESS trial outcomes for IPD meta-analysis of treatment covariate effect
n.iter

Extract the number of iterations for an ipdlme object
tol

Extract the convergence criterion for an ipdlme object
Qt

Measures of covariate heterogeneity
MaxIter

Extract the maximum number of iterations specified for an ipdlme object
confint

Compute confidence intervals for population effects of an ipdlme object
Var

Extract the random effect variance parameters
sigma2

Extract the estimated residual variance for an ipdlme object
regress_age

Aggregated data set of REGRESS trial outcomes for IPD meta-analysis of treatment covariate effect
convergence

Extract the convergence trace for an ipdlme object
VcovFixef

Extract the variance-covariance for the population (fixed effect) estimates for an ipdlme object
ipdlme-class

Class for representing ipdlme objects