Meta-analysis of 31 randomized controled trials (RCTs) of two treatment groups of heart disease patients, where the treatment group received bone marrow stem cells and the control group a placebo treatment.
A matrix with 31 rows and 11 columns. Each row represents study results, the columns are:
ID name of the trial.
treatment effect is measured as the difference of the ejection fraction between groups, which measures the improvement of left ventricular function in the heart.
Standard Error of the effect.size.
Total number of patients in the trial.
Number of detected discrepancies in the published trial. Discrepancies are defined as two or more reported facts that cannot both be true because they are logically or mathematically incompatible.
Bias arising from the randomization process.
Bias due to deviations from intended interventions.
Bias introduced by lack of blinding.
Bias in measurement of the outcome.
Bias in selection of the reported result.
Selection bias, performance bias, detection bias, attrition bias, etc.
Verde, P. E. (2017) Two Examples of Bayesian Evidence Synthesis with the Hierarchical Meta-Regression Approach. Chap.9, pag 189-206. Bayesian Inference, ed. Tejedor, Javier Prieto. InTech.