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jarbes (version 2.4.2)

macula_rwe: Meta-analysis: 83 observational studies assessing the effectiveness of intravitreal therapy for diabetic maculaedema

Description

Meta-analysis of 82 studies comparing 12-month visual acuity change results in routine clinical practices of intravitreal therapy for diabetic maculaedema (DME) to the change in RCTs by pooling data published in the last decade on treated eyes of treatment effect from OS.

Arguments

Format

A dataframe with 83 rows and 24 columns. Each row represents study results, the columns are:

therapy

Used Medication

author_year

Author and year.

study_design

Study type/Design

eyes

Number of tested eyes.

TE

Mean Change in Visual Acuity after 12-Months. Where Visual Acuity is measured in VAR (Visual Acuity Rating) score

seTE

Standard Error of the Treatment Effect

lower_95pct_ci

Lower 95prc CI for TE

upper_95pct_ci

Upper 95prc CI for TE

number_of_patients_at_baseline

Number of Patients in Study at Baseline

mean_age

The mean age of patients per study

sd_age

The standard deviation of age of patients per study

se_age

The standard error of age of patients per study

baseline_va

Mean Visual Acuity at Baseline. Where Visual Acuity is measured in VAR (Visual Acuity Rating) score

sd_baseline_va

The standard deviation of Visual Acuity at Baseline. Where Visual Acuity is measured in VAR (Visual Acuity Rating) score

se_baseline_va

The standard error of Visual Acuity at Baseline. Where Visual Acuity is measured in VAR (Visual Acuity Rating) score

12_month_va

Mean Visual Acuity after 12 months. Where Visual Acuity is measured in VAR (Visual Acuity Rating) score

sd_12_month_va

The standard deviation of Visual Acuity after 12 months. Where Visual Acuity is measured in VAR (Visual Acuity Rating) score

se_12_month_va

The standard error of Visual Acuity after 12 months. Where Visual Acuity is measured in VAR (Visual Acuity Rating) score

baseline_cst

Mean Central Subfield Thickness at Baseline

sd_baseline_cst

The standard deviation of Central Subfield Thickness at Baseline

se_baseline_cst

The standard error of Central Subfield Thickness at Baseline

12_month_cst

Mean Central Subfield Thickness after 12 months

sd_12_month_cst

The standard deviation of Central Subfield Thickness after 12 months

se_12_month_cst

The standard error of Central Subfield Thickness after 12 months