mjoint.object


An object returned by the <code>mjoint</code> function, inheriting from class
<code>mjoint</code> and representing a fitted joint model for multivariate
longitudinal and time-to-event data. Objects of this class have methods for
the generic functions <code>coef</code>, <code>logLik</code>, <code>plot</code>, <code>print</code>,
<code>ranef</code>, <code>fixef</code>, <code>summary</code>, <code>AIC</code>, <code>getVarCov</code>,
<code>vcov</code>, <code>confint</code>, <code>sigma</code>, and <code>formula</code>.


multivariate

survival

Fits the joint model proposed by Henderson and colleagues (2000)
<doi:10.1093/biostatistics/1.4.465>, but extended to the case of multiple
continuous longitudinal measures. The time-to-event data is modelled using a
Cox proportional hazards regression model with time-varying covariates. The
multiple longitudinal outcomes are modelled using a multivariate version of the
Laird and Ware linear mixed model. The association is captured by a multivariate
latent Gaussian process. The model is estimated using a Monte Carlo Expectation
Maximization algorithm. This project is funded by the Medical Research Council
(Grant number MR/M013227/1).

mjoint.object: Fitted `mjoint` object

Description

Usage

Arguments

Value

Format

See Also