kidney.epi (version 1.3.0)

egfr.fas.cr_cys: Calculate eGFR by the Full age spectrum (FAS) creatinine-cystatin-based equation

Description

Calculate eGFR by the Full age spectrum (FAS) creatinine-cystatin-based equation

Usage

egfr.fas.cr_cys(
  creatinine,
  cystatin,
  age,
  sex,
  alpha = 0.5,
  creatinine_units = "micromol/l",
  cystatin_units = "mg/L",
  equation_type = "precise",
  label_sex_male = c("Male", 1),
  label_sex_female = c("Female", 0),
  max_age = 100
)

Value

numeric eGFR expressed in ml/min/1.73m².

Arguments

creatinine

Numeric vector. Serum creatinine, could be expressed in "micromol/L", "mmol/L" or "mg/dL". Units of measurement should be defined in variable creatinine_units (if not defined explicitly by user, the default value is "micromol/L").

cystatin

Numeric vector. Serum cystatin, could be expressed in "mg/L" or "nanomol/L". Units of measurement should be defined in variable cystatin_units (if not defined explicitly by user, the default value is "mg/L").

age

Numeric vector. Age, in years.

sex

Vector. The value of variable refers to the parameters label_sex_male and label_sex_female.

alpha

Numeric vector. Alpha coefficient for the combined creatinine-cystatin equation. By default is equal to 0.5.

creatinine_units

Character string. Units in which serum creatinne is expressed. Could be one of the following: "micromol/L", "mmol/L" or "mg/dL".

cystatin_units

Character string. Units in which serum cystatin is expressed. Could be one of the following: "mg/L" or "nanomol/L"

equation_type

Character string. Whether to use "precise" or "simplified" equation.

label_sex_male

List. Label(s) for definition(s) of male sex.

label_sex_female

List. Label(s) for definition(s) of female sex.

max_age

Numeric. Maximal age suitable for the equation application, in years. By default is 100 years, but change this value in case you would like to apply equation to older persons.

Author

Programming: Boris Bikbov https://www.linkedin.com/in/boris-bikbov.

Details

Calculate estimated glomerular filtration rate (eGFR) by the Full age spectrum (FAS) creatinine-cystatin-based equation.

Reference to the equation: Pottel H, Delanaye P, Schaeffner E et al. Estimating glomerular filtration rate for the full age spectrum from serum creatinine and cystatin C. Nephrol Dial Transplant 2017; 32:497–507 doi:10.1093/ndt/gfw425.

Citation: Bikbov B. kidney.epi: Kidney-Related Functions for Clinical and Epidemiological Research. Scientific-Tools.Org, https://Scientific-Tools.Org. DOI: 10.32614/CRAN.package.kidney.epi

Examples

# for a single patient
egfr.fas.cr_cys (creatinine = 1.4, cystatin = 0.8, age = 60,
   sex = "Male", creatinine_units = "mg/dl")
# for a dataset - see vignettes for details
# egfr.fas.cr_cys (creatinine = dta$scr, cystatin = dta$cys,
#  age = dta$age, sex = dta$sex, creatinine_units = "mg/dl")