kidney.epi (version 1.3.0)

egfr.mdrd4: Calculate estimated glomerular filtration rate (eGFR) by MDRD equation

Description

Calculate estimated glomerular filtration rate (eGFR) by MDRD equation

Usage

egfr.mdrd4(
  creatinine,
  age,
  sex,
  ethnicity,
  creatinine_units = "micromol/l",
  creatinine_method = "non-IDMS",
  label_afroamerican = c("Afroamerican"),
  label_sex_male = c("Male", 1),
  label_sex_female = c("Female", 0),
  max_age = 100
)

Value

numeric eGFR expressed in ml/min/1.73m².

Arguments

creatinine

Numeric vector. Serum creatinine, could be expressed in "micromol/L", "mmol/L" or "mg/dL". Units of measurement should be defined in variable creatinine_units (if not defined explicitly by user, the default value is "micromol/L").

age

Numeric vector. Age, in years.

sex

Vector. The value of variable refers to the parameters label_sex_male and label_sex_female.

ethnicity

Vector. Ethnicity, specify in case of African-American patients. The value of variable refers to the parameter label_afroamerican.

creatinine_units

Character string. Units in which serum creatinne is expressed. Could be one of the following: "micromol/L", "mmol/L" or "mg/dL".

creatinine_method

Character string. Creatinine standartisation method in a laboratory. Could be either "IDMS" or "non-IDMS". If not explicitly defined by user, the default assumption is "non-IDMS".

label_afroamerican

List. Label(s) for Afroamerican ethnicity.

label_sex_male

List. Label(s) for definition(s) of male sex.

label_sex_female

List. Label(s) for definition(s) of female sex.

max_age

Numeric. Maximal age suitable for the equation application, in years. By default is 100 years, but change this value in case you would like to apply equation to older persons.

Author

Programming: Boris Bikbov https://www.linkedin.com/in/boris-bikbov.

Details

Calculate estimated glomerular filtration rate (eGFR) by MDRD equation.

Reference to the equation: Levey AS, Coresh J, Greene T, et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Annals of Internal Medicine 2006;145:247–54.

Citation: Bikbov B. kidney.epi: Kidney-Related Functions for Clinical and Epidemiological Research. Scientific-Tools.Org, https://Scientific-Tools.Org. DOI: 10.32614/CRAN.package.kidney.epi

Examples

# for a single patient
egfr.mdrd4 (creatinine = 1.4, age = 60, sex = "Male", ethnicity = "White",
  creatinine_units = "mg/dl")
# for a dataset - see vignettes for details
# egfr.mdrd4 (creatinine = dta$scr, age = dta$age, sex = dta$sex,
#  ethnicity = dta$race, creatinine_units = "mg/dl")