kin.data


  Simulated data of a study on the penetrance of breast cancer for carriers 2 mutations.


datasets

Analysis of kin-cohort studies. kin.cohort provides estimates of age-specific
cumulative risk of a disease for carriers and noncarriers of a mutation. The cohorts are
retrospectively built from relatives of probands for whom the genotype is known. Currently
the method of moments and marginal maximum likelihood are implemented. Confidence intervals
are calculated from bootstrap samples.
Most of the code is a translation from previous 'MATLAB' code by N. Chatterjee.

Victor Moreno

kin.cohort

Analysis of Kin-Cohort Studies

kin.data function

A data frame with 15341 observations on the following 5 variables.
  <dl>
    <dt><code>age</code></dt><dd>age at diagnosis or at last follow-up</dd> <dt><code>cancer</code></dt><dd>disease status (1: breast cancer, 0: no breast cancer</dd> <dt><code>gen1</code></dt><dd>gen1 genotypes of proband</dd> <dt><code>gen2</code></dt><dd>gen2 genotypes of proband</dd> <dt><code>rel</code></dt><dd>relationship with proband 1:parent or offspring, 2:sibling</dd> <dt><code>family</code></dt><dd>family id</dd> </dl> 

kin.data: sample data for kin-cohort analysis

Description

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Examples