serotonin

<p>This simulated data mimics a PET imaging study where the 5-HT2A
receptor and serotonin transporter (SERT) binding potential has
been quantified into 8 different regions. The 5-HT2A
cortical regions are considered high-binding regions
measurements.  These measurements can be regarded as proxy measures of
the extra-cellular levels of serotonin in the brain</p><table class="table">
<tr><td>day</td><td>numeric</td><td>Scan day of the year</td></tr>
<tr><td>age</td><td>numeric</td><td>Age at baseline scan</td></tr>
<tr><td>mem</td><td>numeric</td><td>Memory performance score</td></tr>
<tr><td>depr</td><td>numeric</td><td>Depression (mild) status 500 days after baseline</td></tr>
<tr><td>gene1</td><td>numeric</td><td>Gene marker 1 (HTR2A)</td></tr>
<tr><td>gene2</td><td>numeric</td><td>Gene marker 2 (HTTTLPR)</td></tr>
<tr><td>cau</td><td>numeric</td><td>SERT binding, Caudate Nucleus</td></tr>
<tr><td>th</td><td>numeric</td><td>SERT binding, Thalamus</td></tr>
<tr><td>put</td><td>numeric</td><td>SERT binding, Putamen</td></tr>
<tr><td>mid</td><td>numeric</td><td>SERT binding, Midbrain</td></tr>
<tr><td>aci</td><td>numeric</td><td>5-HT2A binding, Anterior cingulate gyrus</td></tr>
<tr><td>pci</td><td>numeric</td><td>5-HT2A binding, Posterior cingulate gyrus</td></tr>
<tr><td>sfc</td><td>numeric</td><td>5-HT2A binding, Superior frontal cortex</td></tr>
<tr><td>par</td><td>numeric</td><td>5-HT2A binding, Parietal cortex</td></tr>
</table><p></p><p></p>

datasets

A general implementation of Structural Equation Models
with latent variables (MLE, 2SLS, and composite likelihood
estimators) with both continuous, censored, and ordinal
outcomes (Holst and Budtz-Joergensen (2013) <doi:10.1007/s00180-012-0344-y>).
Mixture latent variable models and non-linear latent variable models
(Holst and Budtz-Joergensen (2020) <doi:10.1093/biostatistics/kxy082>).
The package also provides methods for graph exploration (d-separation,
back-door criterion), simulation of general non-linear latent variable
models, and estimation of influence functions for a broad range of
statistical models.

Klaus Holst

lava

Latent Variable Models

Klaus K. Holst

Brice Ozenne

Thomas Gerds

serotonin function

Format

<p>This simulated data mimics a PET imaging study where the 5-HT2A
receptor and serotonin transporter (SERT) binding potential has
been quantified into 8 different regions. The 5-HT2A
cortical regions are considered high-binding regions
measurements.  These measurements can be regarded as proxy measures of
the extra-cellular levels of serotonin in the brain</p><table class='table'>
<tr><td>day</td><td>numeric</td><td>Scan day of the year</td></tr>
<tr><td>age</td><td>numeric</td><td>Age at baseline scan</td></tr>
<tr><td>mem</td><td>numeric</td><td>Memory performance score</td></tr>
<tr><td>depr</td><td>numeric</td><td>Depression (mild) status 500 days after baseline</td></tr>
<tr><td>gene1</td><td>numeric</td><td>Gene marker 1 (HTR2A)</td></tr>
<tr><td>gene2</td><td>numeric</td><td>Gene marker 2 (HTTTLPR)</td></tr>
<tr><td>cau</td><td>numeric</td><td>SERT binding, Caudate Nucleus</td></tr>
<tr><td>th</td><td>numeric</td><td>SERT binding, Thalamus</td></tr>
<tr><td>put</td><td>numeric</td><td>SERT binding, Putamen</td></tr>
<tr><td>mid</td><td>numeric</td><td>SERT binding, Midbrain</td></tr>
<tr><td>aci</td><td>numeric</td><td>5-HT2A binding, Anterior cingulate gyrus</td></tr>
<tr><td>pci</td><td>numeric</td><td>5-HT2A binding, Posterior cingulate gyrus</td></tr>
<tr><td>sfc</td><td>numeric</td><td>5-HT2A binding, Superior frontal cortex</td></tr>
<tr><td>par</td><td>numeric</td><td>5-HT2A binding, Parietal cortex</td></tr>
</table>



Serotonin data — serotonin

Serotonin data

serotonin: Serotonin data

Description

Arguments

Format

day	numeric	Scan day of the year
age	numeric	Age at baseline scan
mem	numeric	Memory performance score
depr	numeric	Depression (mild) status 500 days after baseline
gene1	numeric	Gene marker 1 (HTR2A)
gene2	numeric	Gene marker 2 (HTTTLPR)
cau	numeric	SERT binding, Caudate Nucleus
th	numeric	SERT binding, Thalamus
put	numeric	SERT binding, Putamen
mid	numeric	SERT binding, Midbrain
aci	numeric	5-HT2A binding, Anterior cingulate gyrus
pci	numeric	5-HT2A binding, Posterior cingulate gyrus
sfc	numeric	5-HT2A binding, Superior frontal cortex
par	numeric	5-HT2A binding, Parietal cortex