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lme4GS (version 0.1)

'lme4' for Genomic Selection

Description

Flexible functions that use 'lme4' as computational engine for fitting models used in Genomic Selection (GS). GS is a technology used for genetic improvement, and it has many advantages over phenotype-based selection. There are several statistical models that adequately approach the statistical challenges in GS, such as in linear mixed models (LMMs). The 'lme4' is the standard package for fitting linear and generalized LMMs in the R-package, but its use for genetic analysis is limited because it does not allow the correlation between individuals or groups of individuals to be defined. The 'lme4GS' package is focused on fitting LMMs with covariance structures defined by the user, bandwidth selection, and genomic prediction. The new package is focused on genomic prediction of the models used in GS and can fit LMMs using different variance-covariance matrices. Several examples of GS models are presented using this package as well as the analysis using real data. For more details see Caamal-Pat et.al. (2021) .

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Version

Install

install.packages('lme4GS')

Monthly Downloads

154

Version

0.1

License

GPL (>= 2)

Maintainer

Paulino Rodriguez

Last Published

April 8th, 2025

Functions in lme4GS (0.1)

maize.G

Genomic relationship matrix for maize lines
lmerUvcov

Fits a linear mixed model with user specified variance covariance-matrices.
lme4GS-package

lme4 for Genomic Selection
ranefUvcovNew

Obtain BLUPs for new levels of random effects with user specified variance covariance-matrices.
theta_optim

Selection of bandwidth parameter for Gaussian and exponential kernels.
ranefUvcov

Extract the conditional means of the random effects
maize.Pheno

Phenotypical data for the maize dataset
wheat.X

Molecular markers
wheat.sets

Sets for cross validation (CV)
lmerUvcov-class

User defined variance covariance mixed-effects model fits
wheat.Pedigree

Pedigree infomation for 599 wheat lines
wheat.Pheno

Phenotypical data for the wheat dataset