maNormMain
. It only applies when two normalization procedures are combined.maCompNormA()
maCompNormEq()
x
and n
, the spot average log-intensities A and the number of normalization procedures. This latter function returns a matrix of weights for combining two normalization procedures, rows correspond to spots and columns to normalization procedures. The weights for the first procedure are given by the empirical cumulative distribution function of the spot average log-intensities A. Note that when performing composite normalization as described in Yang et al. (2002), the first normalization procedure is the global fit and the second procedure is the within-print-tip-group fit.
For maCompEq
, equal weights are given for each procedure.maNormMain
, maNormLoess
, ecdf
.