Price et al. (1985) presented data from a study on the developmental toxicity, 
ethylene glycol (EG),in mice. Responses are the malformation (binary response) and 
fetal weight (continuous response) outcomes for the experiment, which shows clear dose-related trends with respect to both outcomes.

Allows various models for multivariate response variables where each response is assumed to follow double hierarchical generalized linear models. In double hierarchical generalized linear models, the mean, dispersion parameters for variance of random effects, and residual variance can be further modeled as random-effect models.

Maengseok Noh

mdhglm

Multivariate Double Hierarchical Generalized Linear Models

eg function

A data frame with 1028 observations on the following 5 variables.<dl class="dl-horizontal">
 <dt><code>litter</code></dt><dd>litter number for 94 mice</dd>
 <dt><code>dose</code></dt><dd>dose input</dd>
 <dt><code>y1</code></dt><dd>fetal weight (g)</dd>
 <dt><code>y2</code></dt><dd>malformation (0; No, 1; Yes)</dd>
 <dt><code>dose2</code></dt><dd>dose*dose</dd>
 </dl>

Format

Ethylene Glycol Data — eg

A data frame with 1028 observations on the following 5 variables.<dl class='dl-horizontal'>
 <dt><code>litter</code></dt><dd>litter number for 94 mice</dd>
 <dt><code>dose</code></dt><dd>dose input</dd>
 <dt><code>y1</code></dt><dd>fetal weight (g)</dd>
 <dt><code>y2</code></dt><dd>malformation (0; No, 1; Yes)</dd>
 <dt><code>dose2</code></dt><dd>dose*dose</dd>
 </dl>

eg: Ethylene Glycol Data

Description

Usage

Arguments

Format

References