Mean simulation parameters obtained from the analysis of a real dataset
data(param)A data frame with 26408 observations on the following 3 variables.
mucond1a numeric vector with mean parameters for condition 1
mucond2a numeric vector with mean parameters for condition 2
DEa logical vector indicating which tags are differentially expressed (value 1)
Mean parameters provided in this package are empirical means (obtained after normalization for library size differences) of real data described in the following references.
M.A. Dillies, A. Rau, J. Aubert, C. Hennequet-Antier, M. Jeanmougin, N. Servant, C. Keime, G. Marot, D. Castel, J. Estelle, G. Guernec, B. Jagla, L. Jouneau, D. Laloe, C. Le Gall, B. Schaeffer, S. Le Crom, M. Guedj and F. Jaffrezic, on behalf of the French StatOmique Consortium (2013) A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis. Briefings in Bioinformatics 14(6):671-83 .
T. Strub, S. Giuliano, T. Ye, et al. (2011) Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma. Oncogene 30:2319-32.