metaSEM (version 0.9.4)

BCG: Dataset on the Effectiveness of the BCG Vaccine for Preventing Tuberculosis

Description

This dataset includes 13 studies on the effectiveness of the Bacillus Calmette-Guerin (BCG) vaccine for preventing tuberculosis (see van Houwelingen, Arends, & Stijnen (2002) for details).

Usage

data(BCG)

source

Colditz, G. A., Brewer, T. F., Berkey, C. S., Wilson, M. E., Burdick, E., Fineberg, H. V., & Mosteller, F. (1994). Efficacy of BCG vaccine in the prevention of tuberculosis: Meta-analysis of the published literature. Journal of the American Medical Association, 271, 698--702.

Details

A list of data with the following structure: [object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

References

Berkey, C. S., Hoaglin, D. C., Mosteller, F., & Colditz, G. A. (1995). A random-effects regression model for meta-analysis. Statistics in Medicine, 14, 395--411.

van Houwelingen, H. C., Arends, L. R., & Stijnen, T. (2002). Advanced methods in meta-analysis: Multivariate approach and meta-regression. Statistics in Medicine, 21, 589--624.

Viechtbauer, W. (2010). Conducting meta-analyses in R with the metafor package. Journal of Statistical Software, 36(3), 1--48. http://www.jstatsoft.org/v36/i03/.

Examples

data(BCG)

## Univariate meta-analysis on the log of the odds ratio
summary( meta(y=ln_OR, v=v_ln_OR, data=BCG,
              x=cbind(scale(Latitude,scale=FALSE),
              scale(Year,scale=FALSE))) )

## Multivariate meta-analysis on the log of the odds
## The conditional sampling covariance is 0
bcg <- meta(y=cbind(ln_Odd_V, ln_Odd_NV), data=BCG,
            v=cbind(v_ln_Odd_V, cov_V_NV, v_ln_Odd_NV))
summary(bcg)

plot(bcg)