cholesterol

A data set containing clinical trial on hypercholesterolemia including 26 trials and 2 treatment arms each, and other attributes of the participants

datasets

Contains functions performing Bayesian inference for meta-analytic and network meta-analytic models through Markov chain Monte Carlo algorithm. Currently, the package implements Hui Yao, Sungduk Kim, Ming-Hui Chen, Joseph G. Ibrahim, Arvind K. Shah, and Jianxin Lin (2015) <doi:10.1080/01621459.2015.1006065> and Hao Li, Daeyoung Lim, Ming-Hui Chen, Joseph G. Ibrahim, Sungduk Kim, Arvind K. Shah, Jianxin Lin (2021) <doi:10.1002/sim.8983>. For maximal computational efficiency, the Markov chain Monte Carlo samplers for each model, written in C++, are fine-tuned. This software has been developed under the auspices of the National Institutes of Health and Merck & Co., Inc., Kenilworth, NJ, USA.

Daeyoung Lim

metapack

Bayesian Meta-Analysis and Network Meta-Analysis

Ming-Hui Chen

Sungduk Kim

Joseph Ibrahim

Arvind Shah

Jianxin Lin

cholesterol function

A data frame with 52 rows and 19 variables<dl>
	<dt>study</dt>
<dd>study identifier</dd>	<dt>trial</dt>
<dd>trial identifier</dd>	<dt>treat</dt>
<dd>treatment indicator for Statin or Statin+Ezetimibe</dd>	<dt>n</dt>
<dd>the number of participants in the study arms corresponding to the trial and treatment</dd>	<dt>pldlc</dt>
<dd>aggregate percentage change in LDL-C</dd>	<dt>phdlc</dt>
<dd>aggregate percentage change from baseline in HDL-C</dd>	<dt>ptg</dt>
<dd>aggregate percentage change from baseline in triglycerides (TG)</dd>	<dt>sdldl</dt>
<dd>sample standard deviation of percentage change in LDL-C</dd>	<dt>sdhdl</dt>
<dd>sample standard deviation of percentage change in HDL-C</dd>	<dt>sdtg</dt>
<dd>sample standard deviation of percentage change in triglycerides (TG)</dd>	<dt>onstat</dt>
<dd>whether the participants were on Statin prior to the trial</dd>	<dt>bldlc</dt>
<dd>baseline LDL-C</dd>	<dt>bhdlc</dt>
<dd>baseline HDL-C</dd>	<dt>btg</dt>
<dd>baseline triglycerides (TG)</dd>	<dt>age</dt>
<dd>age in years</dd>	<dt>white</dt>
<dd>the proportion of white participants</dd>	<dt>male</dt>
<dd>the proportion of male participants</dd>	<dt>dm</dt>
<dd>the proportion of participants with diabetes mellitus</dd>	<dt>durat</dt>
<dd>duration in weeks</dd>
</dl>

Format

26 double-blind, randomized, active, or placebo-controlled clinical trials on patients with primary hypercholesterolemia sponsored by Merck &amp; Co., Inc., Kenilworth, NJ, USA. — cholesterol

A data frame with 52 rows and 19 variables<dl>
	<dt>study</dt>
<dd>study identifier</dd>

	<dt>trial</dt>
<dd>trial identifier</dd>

	<dt>treat</dt>
<dd>treatment indicator for Statin or Statin+Ezetimibe</dd>

	<dt>n</dt>
<dd>the number of participants in the study arms corresponding to the trial and treatment</dd>

	<dt>pldlc</dt>
<dd>aggregate percentage change in LDL-C</dd>

	<dt>phdlc</dt>
<dd>aggregate percentage change from baseline in HDL-C</dd>

	<dt>ptg</dt>
<dd>aggregate percentage change from baseline in triglycerides (TG)</dd>

	<dt>sdldl</dt>
<dd>sample standard deviation of percentage change in LDL-C</dd>

	<dt>sdhdl</dt>
<dd>sample standard deviation of percentage change in HDL-C</dd>

	<dt>sdtg</dt>
<dd>sample standard deviation of percentage change in triglycerides (TG)</dd>

	<dt>onstat</dt>
<dd>whether the participants were on Statin prior to the trial</dd>

	<dt>bldlc</dt>
<dd>baseline LDL-C</dd>

	<dt>bhdlc</dt>
<dd>baseline HDL-C</dd>

	<dt>btg</dt>
<dd>baseline triglycerides (TG)</dd>

	<dt>age</dt>
<dd>age in years</dd>

	<dt>white</dt>
<dd>the proportion of white participants</dd>

	<dt>male</dt>
<dd>the proportion of male participants</dd>

	<dt>dm</dt>
<dd>the proportion of participants with diabetes mellitus</dd>

	<dt>durat</dt>
<dd>duration in weeks</dd>


</dl>

26 double-blind, randomized, active, or placebo-controlled clinical trials on patients with primary hypercholesterolemia sponsored by Merck &amp; Co., Inc., Kenilworth, NJ, USA.

cholesterol: 26 double-blind, randomized, active, or placebo-controlled clinical trials on patients with primary hypercholesterolemia sponsored by Merck & Co., Inc., Kenilworth, NJ, USA.

Description

Usage

Arguments

Format

Examples