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metaseqR (version 1.12.2)

get.ucsc.annotation: UCSC/RefSeq annotation downloader

Description

This function connects to the UCSC Genome Browser public database and downloads annotation elements (gene co-ordinates, exon co-ordinates, gene identifications etc.) for each of the supported organisms, but using UCSC instead of Ensembl. See the help page of metaseqr for a list of supported organisms. The function downloads annotation for an organism genes or exons.

Usage

get.ucsc.annotation(org, type, refdb="ucsc",
        multic=FALSE)

Arguments

org
the organism for which to download annotation.
type
either "gene" or "exon".
refdb
either "ucsc" or "refseq".
multic
a logical value indicating the presence of multiple cores. Defaults to FALSE. Do not change it if you are not sure whether package parallel has been loaded or not. It is used in the case of type="exon" to process the return value of the query to the UCSC Genome Browser database.

Value

  • A data frame with the canonical (not isoforms!) genes or exons of the requested organism. When type="genes", the data frame has the following columns: chromosome, start, end, gene_id, gc_content, strand, gene_name, biotype. When type="exon" the data frame has the following columns: chromosome, start, end, exon_id, gene_id, strand, gene_name, biotype. The gene_id and exon_id correspond to UCSC or RefSeq gene and exon accessions respectively. The gene_name corresponds to HUGO nomenclature gene names.

Examples

Run this code
hg19.genes <- get.ucsc.annotation("hg19","gene","ucsc")
mm9.exons <- get.ucsc.annotation("mm9","exon","refseq")

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