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metaseqR (version 1.12.2)

mlfo: MLE dispersion estimate

Description

MLE function used to estimate negative binomial dispersions from real RNA-Seq data, as in (Soneson and Delorenzi, BMC Bioinformatics, 2013) and (Robles et al., BMC Genomics, 2012). Internal use.

Usage

mlfo(phi, y)

Arguments

phi
the parameter to be optimized.
y
count samples used to perform the optimization.

Value

  • The objective function value.

Examples

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