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methyAnalysis (version 1.14.0)

estimateCMR.methylation: Estimate the averaged methylation levels within a chromosome region or transcript promoter

Description

Estimate the averaged methylation levels within a chromosome region defined as a GRanges object or transcript promoter

Usage

estimateCMR.methylation(cmr, methyGenoSet, estimateFun = mean, probeAnnotation = NULL, selectGeneElement = c("exon1", "promoter"), mc.cores = min(12, detectCores()))

Arguments

cmr
A GRanges object or transcript ID
methyGenoSet
A MethyGenoSet object keeps the DNA methylation data
estimateFun
The function used to estimate the methylation levels within the chromosome region
probeAnnotation
Pre-calculated probe annotation (a GRanges object)
selectGeneElement
Gene elements used to calculate the transcript promoter methylation levels if cmr GRanges object is not provided.
mc.cores
Number of cores used to calculate in parallel

Value

A numeric matrix (row: cmr, column: samples)

Details

Examples

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