methylKit (version 0.9.5)

normalizeCoverage: normalize read coverage between samples

Description

The function normalizes coverage values between samples using a scaling factor derived from differences between mean or median of coverage distributions

Usage

normalizeCoverage(obj,method="median")

Arguments

obj

methylRawList object

method

a string "mean" or "median" which denotes median or mean should be used to calculate scaling factor. (Default:median)

Value

a methylRawList object

Examples

# NOT RUN {
data(methylKit)
newObj=normalizeCoverage(methylRawList.obj,method="median")
# }