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mixOmics (version 2.7-1)

Integrate Omics data project

Description

The package supplies two efficients methodologies: regularized CCA and sparse PLS to unravel relationships between two heterogeneous data sets of size (nxp) and (nxq) where the p and q variables are measured on the same samples or individuals n. These data may come from high throughput technologies, such as omics data (e.g. transcriptomics, metabolomics or proteomics data) that require an integrative or joint analysis. However, mixOmics can also be applied to any other large data sets where p + q >> n. rCCA is a regularized version of CCA to deal with the large number of variables. sPLS allows variable selection in a one step procedure and two frameworks are proposed: regression and canonical analysis. Numerous graphical outputs are provided to help interpreting the results.

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Version

Install

install.packages('mixOmics')

Monthly Downloads

113

Version

2.7-1

License

GPL (>= 2)

Maintainer

Kim-Anh Cao

Last Published

May 28th, 2010

Functions in mixOmics (2.7-1)

plotIndiv

Plot of Individuals (Experimental Units)
plot3dVar

Plot of Variables in three dimensions
s.match

Plot of Paired Coordinates
nipals

Non-linear Iterative Partial Least Squares (NIPALS) algorithm
cim

Clustered Image Maps (CIMs) ("heat maps")
plsda

Partial Least Squares Discriminate Analysis (PLS-DA).
imgCor

Image Maps of Correlation Matrices between two Data Sets
vip

Variable Importance in the Projection (VIP)
rcc-internal

Regularized CCA Internal Functions
estim.regul

Estimate the parameters of regularization for Regularized CCA
jet.colors

Jet Colors Palette
image

Plot the cross-validation score.
pca

Principal Components Analysis
plot.rcc

Canonical Correlations Plot
spls

Sparse Partial Least Squares (sPLS)
multidrug

Multidrug Resistence Data
valid

Compute validation criterion for PLS and Sparse PLS
scatterutil

Graphical utility functions from ade4
liver.toxicity

Liver Toxicity Data
plot3dIndiv

Plot of Individuals (Experimental Units) in three dimensions
linnerud

Linnerud Dataset
network

Relevance Network for (Regularized) CCA and (sparse) PLS regression
rcc

Regularized Canonical Correlation Analysis
breast.tumors

Human Breast Tumors Data
print

Print Methods for CCA, (s)PLS and Summary objects
predict

Predict Method for PLS Regression and Sparse PLS
splsda

Sparse Partial Least Squares Discriminate Analysis (sPLS-DA)
pls

Partial Least Squares (PLS) Regression
plotVar

Plot of Variables
mat.rank

Matrix Rank
summary

Summary Methods for CCA and PLS objects
nutrimouse

Nutrimouse Dataset