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mixtNB (version 1.0)

DE Analysis of RNA-Seq Data by Mixtures of NB

Description

Differential expression analysis of RNA-Seq data when replicates under two conditions are available is performed. First, mixtures of Negative Binomial distributions are fitted on the data in order to estimate the dispersions, then the Wald test is computed.

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Version

Install

install.packages('mixtNB')

Monthly Downloads

4

Version

1.0

License

GPL-3

Maintainer

Cinzia Viroli

Last Published

May 2nd, 2015

Functions in mixtNB (1.0)

filter.em

Internal function that perform pre-filtering
fun.a

Internal function for the Newton-Raphson step of the EM algorithm
wald.test

Wald test for performing DE analysis
mixtNB-package

DE Analysis of RNA-Seq Data by Mixtures of Negative Binomials
fit.mixtNB

Fitting mixtures of Negative Binomials in RNA-Seq data