A data set simulated under the planning assumptions for a study comparing four radiation regimens for a photodynamic
treatment of actinic keratosis. Each patient receives each treatment in a different skin patch and each patch contains four lesions.
Variables are patient identifier (id), treatment (trt), lesion identifier within a patient (lesion), the binary outcome clearance success (1=success, 0=no success)
reported for each lesion and the metric outcome pain (larger values indicating more pain) reported for each skin patch. The aim of the study is to compare
the treatments B, C and D to the reference treatment A in terms of both outcomes.