app_server

These guidelines are meant to provide a pragmatic, yet rigorous, help to drug developers and decision makers, since they are shaped by three fundamental ingredients: the clinically determined margin of detriment on OS that is unacceptably high (delta null); the benefit on OS that is plausible given the mechanism of action of the novel intervention (delta alt); and the quantity of information (i.e. survival events) it is feasible to accrue given the clinical and drug development setting. The proposed guidelines facilitate transparent discussions between stakeholders focusing on the risks of erroneous decisions and what might be an acceptable trade-off between power and the false positive error rate.

Thibaud Coroller

monitOS

Monitoring Overall Survival in Pivotal Trials in Indolent
Cancers

Thomas Fleming

Lisa Hampson

Bharani Bharani-Dharan

Frank Bretz

Arunava Chakravartty

Evanthia Koukouli

Janet Wittes

Nigel Yateman

Emmanuel Zuber

Novartis Pharma AG

app_server function

<dl><dt>input</dt>
<dd>generic shiny var</dd>
<dt>output</dt>
<dd>generic shiny var</dd>
<dt>session</dt>
<dd>generic shiny var</dd></dl>

Arguments

Shiny app server — app_server

<dl>

<dt>input</dt>
<dd>generic shiny var</dd>


<dt>output</dt>
<dd>generic shiny var</dd>


<dt>session</dt>
<dd>generic shiny var</dd>

</dl>

Shiny app server

app_server: Shiny app server

Description

Usage

Arguments