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monocle3 (version 0.1.3)

fit_models: Fits a model for each gene in a cell_data_set object.

Description

This function fits a generalized linear model for each gene in a cell_data_set. Formulae can be provided to account for additional covariates (e.g. day collected, genotype of cells, media conditions, etc).

Usage

fit_models(cds, model_formula_str, expression_family = "quasipoisson",
  reduction_method = "UMAP", cores = 1, clean_model = TRUE,
  verbose = FALSE, ...)

Arguments

cds

The cell_data_set upon which to perform this operation.

model_formula_str

A formula string specifying the model to fit for the genes.

expression_family

Specifies the family function used for expression responses. Default is "quasipoisson".

reduction_method

Which method to use with clusters() and partitions(). Default is "UMAP".

cores

The number of processor cores to use during fitting.

clean_model

Logical indicating whether to clean the model. Default is TRUE.

verbose

Logical indicating whether to emit progress messages.

...

Additional arguments passed to model fitting functions.

Value

a tibble containing model objects