.getStiff

internal

'Monolix' is a tool for running mixed effects model using
'saem'. This tool allows you to convert 'Monolix' models to 'rxode2'
(Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) using the
form compatible with 'nlmixr2' (Fidler et al (2019) <doi:10.1002/psp4.12445>).
If available, the 'rxode2' model will
read in the 'Monolix' data and compare the simulation for the
population model individual model and residual
model to immediately show how well the translation is
performing. This saves the model development time for people who are
creating an 'rxode2' model manually. Additionally, this package reads
in all the information to allow simulation with uncertainty (that is the
number of observations, the number of subjects, and the covariance
matrix) with a 'rxode2' model. This is complementary to the
'babelmixr2' package that translates 'nlmixr2' models to 'Monolix' and can
convert the objects converted from 'monolix2rx' to a full 'nlmixr2' fit. While not
required, you can get/install the 'lixoftConnectors' package in the 'Monolix'
installation, as described at the following url <https://monolixsuite.slp-software.com/r-functions/2024R1/installation-and-initialization>. When
'lixoftConnectors' is available, 'Monolix' can be used to load its model library
instead manually setting up text files (which only works with old versions of
'Monolix').

Matthew Fidler

monolix2rx

Converts 'Monolix' Models to 'rxode2'

Justin Wilkins

.getStiff function

<dl><dt>x</dt>
<dd>monolix2rx object</dd></dl>

Arguments

Author

Get if the model object is stiff — .getStiff

<dl>

<dt>x</dt>
<dd>monolix2rx object</dd>

</dl>

.getStiff: Get if the model object is stiff

Description

Usage

Value

Arguments

Author