recmatrix

object that can be coerced to numeric with <code><a rd-options="" href="/link/stime?package=mrgsolve&version=0.8.9" data-mini-rdoc="mrgsolve::stime">stime</a></code>

times

if <code>TRUE</code>, compartment numbers will be decremented by 1

c_indexing

This function is for use with <code><a rd-options="" href="/link/qsim?package=mrgsolve&version=0.8.9" data-mini-rdoc="mrgsolve::qsim">qsim</a></code> only.

Facilitates simulation from hierarchical, ordinary
differential equation (ODE) based models typically employed in drug development.
A model specification file is created consisting of R and C++ code that
is parsed, compiled, and dynamically loaded into the R session. Input data are
passed in and simulated data are returned as R objects. A dosing event engine
allows interventions (bolus and infusion) to be managed separately from the
model code. Differential equations are solved with the 'DLSODA' routine
in 'ODEPACK' (<https://computation.llnl.gov/casc/odepack/>).

Kyle T Baron

mrgsolve

Simulate from ODE-Based Population PK/PD and Systems
Pharmacology Models

Alan C Hindmarsh

Linda R Petzold

Bill Gillespie

Charles Margossian

Devin Pastoor

Metrum Research Group LLC 

recmatrix function

object that can be coerced to numeric with <code><a rd-options='' href='stime'>stime</a></code>

This function is for use with <code><a rd-options='' href='qsim'>qsim</a></code> only.

recmatrix: Create a matrix of events for simulation.

Description

Usage

Arguments