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msce (version 1.0.2)

msce-package: msce: Hazard of Multi-Stage Clonal Expansion Models

Description

Functions to calculate hazard and survival function of Multi-Stage Clonal Expansion Models used in cancer epidemiology. For the Two-Stage Clonal Expansion Model an exact solution is implemented assuming piecewise constant parameters, see Heidenreich, Luebeck, Moolgavkar (1997) tools:::Rd_expr_doi("10.1111/j.1539-6924.1997.tb00878.x"). Numerical solutions are provided for its extensions, see also Little, Vineis, Li (2008) tools:::Rd_expr_doi("10.1016/j.jtbi.2008.05.027").

Arguments

Author

Maintainer: Cristoforo Simonetto cristoforo.simonetto@ph.tum.de (ORCID)

Other contributors:

  • Jan Christian Kaiser [contributor]