antidepressants

Network meta-analysis comparing antidepressants in patients with major
depressive disorder.

datasets

Estimation of treatment hierarchies in network meta-analysis using a novel frequentist approach based on treatment choice criteria (TCC) and probabilistic ranking models, as described by Evrenoglou et al. (2024) <DOI:10.48550/arXiv.2406.10612>. The TCC are defined using a rule based on the smallest worthwhile difference (SWD). Using the defined TCC, the NMA estimates (i.e., treatment effects and standard errors) are first transformed into treatment preferences, indicating either a treatment preference (e.g., treatment A > treatment B) or a tie (treatment A = treatment B). These treatment preferences are then synthesized using a probabilistic ranking model, which estimates the latent ability parameter of each treatment and produces the final treatment hierarchy. This parameter represents each treatments ability to outperform all the other competing treatments in the network. Here the terms ability to outperform indicates the propensity of each treatment to yield clinically important and beneficial effects when compared to all the other treatments in the network. Consequently, larger ability estimates indicate higher positions in the ranking list.

Theodoros Evrenoglou

mtrank

Ranking using Probabilistic Models and Treatment Choice Criteria

Guido Schwarzer

antidepressants function

A data frame with the following columns:<table class="table">
<tr><td>studyid</td><td>study id</td></tr>
<tr><td>drug_name</td><td>antidepressant name</td></tr>
<tr><td>ntotal</td><td>number of randomized patients in treatment arm</td></tr>
<tr><td>responders</td><td>number of responders</td></tr>
</table>

Format

Network meta-analysis for major depressive disorder — antidepressants

A data frame with the following columns:<table class='table'>
<tr><td>studyid</td><td>study id</td></tr>
<tr><td>drug_name</td><td>antidepressant name</td></tr>
<tr><td>ntotal</td><td>number of randomized patients in treatment arm</td></tr>
<tr><td>responders</td><td>number of responders</td></tr>
</table>

antidepressants: Network meta-analysis for major depressive disorder

Description

Arguments

Format

See Also

Examples

*studyid*	study id
*drug_name*	antidepressant name
*ntotal*	number of randomized patients in treatment arm
*responders*	number of responders