myTAI (version 2.3.4)

stat_reductive_hourglass_test: Reductive Hourglass Test

Description

Test for reductive hourglass patterns in transcriptomic data by comparing early and late developmental stages to mid developmental stages.

Usage

stat_reductive_hourglass_test(phyex_set, modules, ...)

Value

A ConservationTestResult object with reductive hourglass test results

Arguments

phyex_set

A PhyloExpressionSet object

modules

A named list with elements 'early', 'mid', and 'late' containing stage indices for each developmental module

...

Additional arguments passed to stat_generic_conservation_test

Details

The reductive hourglass test evaluates whether mid developmental stages show lower transcriptomic index values (indicating older genes) compared to both early and late stages. This creates an hourglass-shaped pattern where ancient genes dominate during mid-development. The test computes a score based on the minimum difference between early vs. mid and late vs. mid TXI values.

See Also

stat_generic_conservation_test, stat_reverse_hourglass_test

Examples

# Define developmental modules
modules <- list(early = 1:2, mid = 3:5, late = 6:7)
result <- stat_reductive_hourglass_test(example_phyex_set_old, modules=modules)