nca.check.sim: Check simulated data

Description

nca.check.sim Checks simulated data for compatibility with ncappc and processes the data with various filtering criteria.

Usage

nca.check.sim(simData, idNmSim = "ID", timeNmSim = "TIME",
  concNmSim = "DV", filterNm = NULL, filterExcl = NULL,
  str1Nm = NULL, str1 = NULL, str2Nm = NULL, str2 = NULL,
  str3Nm = NULL, str3 = NULL, adminType = "extravascular",
  TI = NULL, doseAmtNm = NULL, blqNm = NULL, blqExcl = 1,
  evid = TRUE, evidIncl = 0, mdv = FALSE)

Value

A list of objects

Arguments

simData: Simulated concentration-time data.
idNmSim: Column name for ID in simulated data. Default is "ID"
timeNmSim: Column name for time in simulated data. Default is "TIME"
concNmSim: Column name for concentration in simulated data. Default is "DV"
filterNm: Column name to filter data. Default is NULL
filterExcl: Row exclusion criteria based on the column defined by filterNm. This can be numeric value or logical condition (e.g. c(1, 2, "<20", ">=100", "!=100")). Default is NULL
str1Nm: Column name for 1st level population stratifier. Default is NULL
str1: Stratification ID of the members within 1st level stratification (e.g c(1,2)). Default is NULL
str2Nm: Column name for 2nd level population stratifier. Default is NULL
str2: Stratification ID of the members within 2nd level stratification (e.g c(1,2)). Default is NULL
str3Nm: Column name for 3rd level population stratifier. Default is NULL
str3: Stratification ID of the members within 3rd level stratification (e.g c(1,2)). Default is NULL
adminType: Route of administration. Allowed options are iv-bolus, iv-infusion or extravascular. Default is "extravascular"
TI: Infusion duration. If TI is a single numeric value, TI is the same for all individuals. If TI is the name of a column with numeric data present in the data set, TI is set to the unique value of the column for a given individual. Default is NULL
doseAmtNm: Column name to specify dose amount. Default is NULL
blqNm: Name of BLQ column if used to exclude data. Default is NULL
blqExcl: Excluded BLQ value; either a numeric value or a logical condition (e.g. 1 or ">=1" or c(1,">3")). Used only if the blqNm is not NULL. Default is "1"
evid: If TRUE EVID is used to filter data. Default is TRUE
evidIncl: Included values in EVID. Default is "0"
mdv: If TRUE MDV is used to include data when MDV=0. Default is FALSE

Details

nca.check.sim Checks simulated data for compatibility with ncappc.