nca.npde

A data frame containing the prediction distribution errors
(PDE) of NCA metrics

pdedata

The range of column numbers in the data frame containing the
PDE values, which will be used to calculate the corresponding NPDE

pdecol

nca.npde calculates individual normalized prediction distribution 
errors (NPDE) of selected NCA metrics from the PDE data.

A flexible tool that can perform
(i) traditional non-compartmental analysis (NCA) and
(ii) Simulation-based posterior predictive checks for population
pharmacokinetic (PK) and/or pharmacodynamic (PKPD) models using NCA metrics.

Andrew C Hooker

ncappc

NCA Calculations and Population Model Diagnosis

Chayan Acharya

Andrew C. Hooker

Gulbeyaz Y. Turkyilmaz

Siv Jonsson

Mats O. Karlsson

nca.npde function

<dl><dt>pdedata</dt>
<dd>A data frame containing the prediction distribution errors
(PDE) of NCA metrics</dd>
<dt>pdecol</dt>
<dd>The range of column numbers in the data frame containing the
PDE values, which will be used to calculate the corresponding NPDE</dd></dl>

Arguments

Calculates individual normalized prediction distribution errors (NPDE) from
PDE data. — nca.npde

<dl>

<dt>pdedata</dt>
<dd>A data frame containing the prediction distribution errors
(PDE) of NCA metrics</dd>


<dt>pdecol</dt>
<dd>The range of column numbers in the data frame containing the
PDE values, which will be used to calculate the corresponding NPDE</dd>

</dl>

nca.npde: Calculates individual normalized prediction distribution errors (NPDE) from PDE data.

Description

Usage

Value

Arguments

Details