RptCfg

Contains the names and order of colum of return table/text by <code>IndiNCA</code>
and <code>NCA</code> functions

dataset

Conduct a noncompartmental analysis as closely as possible to the most widely used commercial software for pharmacokinetic analysis, i.e. 'Phoenix(R) WinNonlin(R)' <https://www.certara.com/software/pkpd-modeling-and-simulation/phoenix-winnonlin/>.
Some features include:
1) Use CDISC SDTM PP domain terms and generate PP domains from DM, EX, and PC domains.
2) Automatic slope selection with the same criterion of WinNonlin(R)
3) Support both 'linear-up linear-down' and 'linear-up log-down' method
4) Calculate partial(interval) AUC with 'linear' or 'log' interpolation method
5) Perform a noncompartmental analysis of CDISC standardized pharmacokinetic dataset (.XPT)
For more details on noncompartmental analysis, see the reference: Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016. (ISBN:9198299107)
*) Acknowledgement: Author thanks for the careful review and valuable input of Dr. Jee Eun Lee.

Sungpil Han

ncar

Noncompartmental Analysis of Pharmacokinetic Data for CDISC
Standardized Parameters

RptCfg function

A data frame with 48 observations on the following 10 variables.
<dl class="dl-horizontal">
<dt>PPTESTCD</dt><dd>a character vector of CDISC SDTM
PPTESTCD</dd> <dt>SYNONYM</dt><dd>a character vector of CDISC SDTM PPTESTCD
Synonym</dd> <dt>NCI</dt><dd>a character vector of NCI peferred terms</dd>
<dt>WNL</dt><dd>a character vector of WinNonlin(R) software variables</dd>
<dt>ExtravascularDefault</dt><dd>a numeric vector of ordering in report
for extravascular administration, Zero means exclusion in the report.</dd>
<dt>ExtravascularWNL</dt><dd>a numeric vector of WinNonlin(R) style
ordering in report for extravascular administration, Zero means exclusion in
the report.</dd> <dt>BolusDefault</dt><dd>a numeric vector of ordering in
report for extravascular administration, Zero means exclusion in the
report.</dd> <dt>BolusWNL</dt><dd>a numeric vector of WinNonlin(R) style
ordering in report for extravascular administration, Zero means exclusion in
the report.</dd> <dt>InfusionDefault</dt><dd>a numeric vector of ordering in
report for extravascular administration, Zero means exclusion in the
report.</dd> <dt>InfusionWNL</dt><dd>a numeric vector of WinNonlin(R) style
ordering in report for extravascular administration, Zero means exclusion in
the report.</dd> </dl>

Format

NCA Report Configuation Table — RptCfg

A data frame with 48 observations on the following 10 variables.
<dl class='dl-horizontal'>
<dt>PPTESTCD</dt><dd>a character vector of CDISC SDTM
PPTESTCD</dd> <dt>SYNONYM</dt><dd>a character vector of CDISC SDTM PPTESTCD
Synonym</dd> <dt>NCI</dt><dd>a character vector of NCI peferred terms</dd>
<dt>WNL</dt><dd>a character vector of WinNonlin(R) software variables</dd>
<dt>ExtravascularDefault</dt><dd>a numeric vector of ordering in report
for extravascular administration, Zero means exclusion in the report.</dd>
<dt>ExtravascularWNL</dt><dd>a numeric vector of WinNonlin(R) style
ordering in report for extravascular administration, Zero means exclusion in
the report.</dd> <dt>BolusDefault</dt><dd>a numeric vector of ordering in
report for extravascular administration, Zero means exclusion in the
report.</dd> <dt>BolusWNL</dt><dd>a numeric vector of WinNonlin(R) style
ordering in report for extravascular administration, Zero means exclusion in
the report.</dd> <dt>InfusionDefault</dt><dd>a numeric vector of ordering in
report for extravascular administration, Zero means exclusion in the
report.</dd> <dt>InfusionWNL</dt><dd>a numeric vector of WinNonlin(R) style
ordering in report for extravascular administration, Zero means exclusion in
the report.</dd> </dl>

RptCfg: NCA Report Configuation Table

Description

Usage

Arguments

Format

Details