ng_vignette

NeuroimaGene data table containing select associations used in the package vignette.

Contains functions to query and visualize the Neuroimaging features
associated with genetically regulated gene expression (GReX). The primary utility,
neuroimaGene(), relies on a list of user-defined genes and returns a table of
neuroimaging features (NIDPs) associated with each gene. This resource
is designed to assist in the interpretation of genome-wide and transcriptome-wide
association studies that evaluate brain related traits. Bledsoe (2024)
<doi:10.1016/j.ajhg.2024.06.002>. In addition there are several visualization
functions that generate summary plots and 2-dimensional visualizations of regional
brain measures. Mowinckel (2020).

Xavier Bledsoe

neuroimaGene

Transcriptomic Atlas of Neuroimaging Derived Phenotypes

Eric Gamazon

ng_vignette function

A data.table with 6 columns and 3824 rows:<dl>
 <dt>gene</dt>
<dd>character: ENSEMBL Gene ID</dd> <dt>gene_name</dt>
<dd>character: HUGO gene name</dd> <dt>gwas_phenotype</dt>
<dd>character: neuroimaging derived phenotype</dd> <dt>training_model</dt>
<dd>character: JTI derived tissue gene expression model</dd> <dt>zscore</dt>
<dd>numeric: normalized effect size of GReX on NIDP morphology</dd> <dt>mod_BHpval</dt>
<dd>character: Benjamini Hochberg corrected pvalue corrected by modality</dd>
</dl>

Format

NeuroimaGene object for vignette illustration — ng_vignette

A data.table with 6 columns and 3824 rows:<dl>
 <dt>gene</dt>
<dd>character: ENSEMBL Gene ID</dd>

 <dt>gene_name</dt>
<dd>character: HUGO gene name</dd>

 <dt>gwas_phenotype</dt>
<dd>character: neuroimaging derived phenotype</dd>

 <dt>training_model</dt>
<dd>character: JTI derived tissue gene expression model</dd>

 <dt>zscore</dt>
<dd>numeric: normalized effect size of GReX on NIDP morphology</dd>

 <dt>mod_BHpval</dt>
<dd>character: Benjamini Hochberg corrected pvalue corrected by modality</dd>


</dl>

ng_vignette: NeuroimaGene object for vignette illustration

Description

Usage

Arguments

Value

Format