VAFselection

<p>This data is generated from an evolutionary model where there is on subclonal population
and all other mutations are neutral passengers.</p>

datasets

Package takes frequencies of mutations as reported by high throughput sequencing data from cancer and fits a theoretical neutral model of tumour evolution. Package outputs summary statistics and contains code for plotting the data and model fits. See Williams et al 2016 <doi:10.1038/ng.3489> and Williams et al 2017 <doi:10.1101/096305> for further details of the method.

Marc Williams

neutralitytestr

Test for a Neutral Evolutionary Model in Cancer Sequencing Data

VAFselection function

<p>A vector with variant allele frequencies (VAFs) ranging from 0 to 1</p>

VAFselection: Synthetic sequencing data generated from a evolutionary based cancer simulation.

Description

Usage

Arguments

Format