gr_network

A data.frame/tibble describing gene regulatory interactions such as TF-target interactions

datasets

This package allows you the investigate intercellular communication from a computational perspective. More specifically, it allows to investigate how interacting cells influence each other's gene expression. Functionalities of this package (e.g. including predicting extracellular upstream regulators and their affected target genes) build upon a probabilistic model of ligand-target links that was inferred by data-integration.

Robin Browaeys

nichenetr

NicheNet: Modeling Intercellular Communication by Linking Ligands to Target Genes

gr_network function

A data frame/tibble<dl class="dl-horizontal">
 <dt>from</dt><dd>regulatory gene</dd>
 <dt>to</dt><dd>target gene</dd>
 <dt>source</dt><dd>name of data source describing the interaction</dd>
 <dt>database</dt><dd>name of the more comprehensive database the data source is part of</dd>
 </dl>

Format

Gene regulatory network — gr_network

A data frame/tibble<dl class='dl-horizontal'>
 <dt>from</dt><dd>regulatory gene</dd>
 <dt>to</dt><dd>target gene</dd>
 <dt>source</dt><dd>name of data source describing the interaction</dd>
 <dt>database</dt><dd>name of the more comprehensive database the data source is part of</dd>
 </dl>

gr_network: Gene regulatory network

Description

Usage

Arguments

Format