lr_network

A data.frame/tibble describing ligand-receptor interactions and the data source describing this interaction.

datasets

This package allows you the investigate intercellular communication from a computational perspective. More specifically, it allows to investigate how interacting cells influence each other's gene expression. Functionalities of this package (e.g. including predicting extracellular upstream regulators and their affected target genes) build upon a probabilistic model of ligand-target links that was inferred by data-integration.

Robin Browaeys

nichenetr

NicheNet: Modeling Intercellular Communication by Linking Ligands to Target Genes

lr_network function

A data frame/tibble<dl class="dl-horizontal">
 <dt>from</dt><dd>the ligand</dd>
 <dt>to</dt><dd>receptor of the ligand</dd>
 <dt>source</dt><dd>name of data source describing the interaction</dd>
 <dt>database</dt><dd>name of the more comprehensive database the data source is part of</dd>
 </dl>

Format

Ligand-receptor network — lr_network

A data frame/tibble<dl class='dl-horizontal'>
 <dt>from</dt><dd>the ligand</dd>
 <dt>to</dt><dd>receptor of the ligand</dd>
 <dt>source</dt><dd>name of data source describing the interaction</dd>
 <dt>database</dt><dd>name of the more comprehensive database the data source is part of</dd>
 </dl>

lr_network: Ligand-receptor network

Description

Usage

Arguments

Format