sig_network

A data.frame/tibble describing gene-gene interactions that are involved in signaling transduction (e.g. PPI, kinase-target,...)

datasets

This package allows you the investigate intercellular communication from a computational perspective. More specifically, it allows to investigate how interacting cells influence each other's gene expression. Functionalities of this package (e.g. including predicting extracellular upstream regulators and their affected target genes) build upon a probabilistic model of ligand-target links that was inferred by data-integration.

Robin Browaeys

nichenetr

NicheNet: Modeling Intercellular Communication by Linking Ligands to Target Genes

sig_network function

A data frame/tibble<dl class="dl-horizontal">
 <dt>from</dt><dd>source gene</dd>
 <dt>to</dt><dd>target gene</dd>
 <dt>source</dt><dd>name of data source describing the interaction</dd>
 <dt>database</dt><dd>name of the more comprehensive database the data source is part of</dd>
 </dl>

Format

Signaling network — sig_network

A data frame/tibble<dl class='dl-horizontal'>
 <dt>from</dt><dd>source gene</dd>
 <dt>to</dt><dd>target gene</dd>
 <dt>source</dt><dd>name of data source describing the interaction</dd>
 <dt>database</dt><dd>name of the more comprehensive database the data source is part of</dd>
 </dl>

sig_network: Signaling network

Description

Usage

Arguments

Format