Learn R Programming

⚠️There's a newer version (3.1-168) of this package.Take me there.

nlme (version 3.1-57)

Linear and nonlinear mixed effects models

Description

Fit and compare Gaussian linear and nonlinear mixed-effects models.

Copy Link

Version

Install

install.packages('nlme')

Monthly Downloads

149,202

Version

3.1-57

License

GPL version 2 or later

Maintainer

Douglas Bates

Last Published

March 31st, 2025

Functions in nlme (3.1-57)

ACF

Autocorrelation Function
ACF.gls

Autocorrelation Function for gls Residuals
Initialize.lmeStruct

Initialize an lmeStruct Object
Dim.pdMat

Dimensions of a pdMat Object
Names.formula

Extract Names from a formula
Variogram.default

Calculate Semi-variogram
Dim.corSpatial

Dimensions of a corSpatial Object
Variogram.corSpatial

Calculate Semi-variogram for a corSpatial Object
LDEsysMat

Generate system matrix for LDEs
Dim.corStruct

Dimensions of a corStruct Object
Variogram.corRatio

Calculate Semi-variogram for a corRatio Object
fitted.lme

Extract lme Fitted Values
corLin

Linear Correlation Structure
Covariate

Assign Covariate Values
Variogram.corExp

Calculate Semi-variogram for a corExp Object
getGroupsFormula

Extract Grouping Formula
balancedGrouped

Create a groupedData object from a matrix
Coef

Assign Values to Coefficients
Names.pdBlocked

Names of a pdBlocked Object
collapse.groupedData

Collapse a groupedData Object
asOneFormula

Combine Formulas of a Set of Objects
allCoef

Extract Coefficients from a Set of Objects
VarCorr

Extract variance and correlation components
Variogram.corSpher

Calculate Semi-variogram for a corSpher Object
Initialize.varFunc

Initialize varFunc Object
compareFits

Compare Fitted Objects
Names.pdMat

Names of a pdMat Object
as.matrix.reStruct

Matrices of an reStruct Object
Initialize.corStruct

Initialize corStruct Object
corCAR1

Continuous AR(1) Correlation Structure
corMatrix.reStruct

Extract Correlation Matrix from Components of an reStruct Object
anova.lme

Compare Likelihoods of Fitted Objects
coef.varFunc

varFunc Object Coefficients
asTable

Convert groupedData to a matrix
Covariate.varFunc

Assign varFunc Covariate
lmList

List of lm Objects with a Common Model
Matrix.reStruct

Assign reStruct Matrices
coef.gnls

Extract gnls Coefficients
ACF.lme

Autocorrelation Function for lme Residuals
fitted.lmeStruct

Calculate lmeStruct Fitted Values
comparePred

Compare Predictions
corCompSymm

Compound Symmetry Correlation Structure
Variogram.corLin

Calculate Semi-variogram for a corLin Object
corFactor

Factor of a Correlation Matrix
corExp

Exponential Correlation Structure
corMatrix

Extract Correlation Matrix
lmeControl

Control Values for lme Fit
nlmeObject

Fitted nlme Object
getVarCov

Extract variance-covariance matrix
formula.reStruct

Extract reStruct Object Formula
Variogram.lme

Calculate Semi-variogram for Residuals from an lme Object
fixed.effects

Extract Fixed Effects
Matrix

Assign Matrix Values
coef.corStruct

Coefficients of a corStruct Object
corMatrix.corStruct

Matrix of a corStruct Object
Variogram

Calculate Semi-variogram
fitted.nlmeStruct

Calculate nlmeStruct Fitted Values
gnlsControl

Control Values for gnls Fit
fdHess

Finite difference Hessian
getData.lmList

Extract lmList Object Data
getGroups.lmList

Extract lmList Object Groups
corMatrix.pdMat

Extract Correlation Matrix from a pdMat Object
contr.SAS

Contrast Matrices
augPred

Augmented Predictions
lme.lmList

LME fit from lmList Object
corFactor.corStruct

Factor of a corStruct Object Matrix
corSymm

General Correlation Structure
getGroups.gls

Extract gls Object Groups
getGroups.corStruct

Extract corStruct Groups
glsStruct

Generalized Least Squares Structure
isBalanced

Check a Design for Balance
coef.reStruct

reStruct Object Coefficients
corClasses

Correlation Structure Classes
fitted.glsStruct

Calculate glsStruct Fitted Values
pdMatrix.reStruct

Extract Matrix or Square-Root Factor from Components of an reStruct Object
logLik.lmList

Log-Likelihood of an lmList Object
corGaus

Gaussian Correlation Structure
corSpher

Spherical Correlation Structure
anova.gls

Compare Likelihoods of Fitted Objects
getCovariateFormula

Extract Covariates Formula
BIC

Bayesian Information Criterion
glsControl

Control Values for gls Fit
logLik.corStruct

Extract corStruct Log-Likelihood
BIC.logLik

BIC of a logLik Object
getCovariate

Extract Covariate from an Object
coef.lmList

Extract lmList Coefficients
gapply

Apply a Function by Groups
corAR1

AR(1) Correlation Structure
getCovariate.data.frame

Extract Data Frame Covariate
getCovariate.varFunc

Extract varFunc Covariate
gnls

Fit Nonlinear Model Using Generalized Least Squares
glsObject

Fitted gls Object
formula.pdBlocked

Extract pdBlocked Formula
lme

Linear Mixed-Effects Models
[.pdMat

Subscript a pdMat Object
pdBlocked

Positive-Definite Block Diagonal Matrix
getData.gls

Extract gls Object Data
coef.pdMat

pdMat Object Coefficients
pdSymm

General Positive-Definite Matrix
model.matrix.reStruct

reStruct Model Matrix
getData.lme

Extract lme Object Data
getResponseFormula

Extract Formula Specifying Response Variable
fitted.gnlsStruct

Calculate gnlsStruct Fitted Values
pdCompSymm

Positive-Definite Matrix with Compound Symmetry Structure
lmList.groupedData

lmList Fit from a groupedData Object
groupedData

Construct a groupedData Object
pooledSD

Extract Pooled Standard Deviation
corRatio

Rational Quadratic Correlation Structure
Matrix.pdMat

Assign Matrix to a pdMat Object
pdFactor.reStruct

Extract Square-Root Factor from Components of an reStruct Object
pdMatrix

Extract Matrix or Square-Root Factor from a pdMat Object
getGroups.varFunc

Extract varFunc Groups
nlme.nlsList

NLME fit from nlsList Object
varFunc

Variance Function Structure
solve.reStruct

Apply Solve to an reStruct Object
logLik.glsStruct

Log-Likelihood of a glsStruct Object
pdDiag

Diagonal Positive-Definite Matrix
logLik.lme

Log-Likelihood of an lme Object
Names

Names Associated with an Object
lmeObject

Fitted lme Object
plot.lmList

Plot an lmList Object
pdIdent

Multiple of the Identity Positive-Definite Matrix
intervals

Confidence Intervals on Coefficients
predict.lmList

Predictions from an lmList Object
pdMat

Positive-Definite Matrix
ranef.lme

Extract lme Random Effects
residuals.lme

Extract lme Residuals
pairs.lme

Pairs Plot of an lme Object
quinModel

Model function for the Quinidine data
corNatural

General correlation in natural parameterization
predict.nlme

Predictions from an nlme Object
gsummary

Summarize by Groups
nlmeStruct

Nonlinear Mixed-Effects Structure
plot.ranef.lmList

Plot a ranef.lmList Object
getGroups

Extract Grouping Factors from an Object
plot.lme

Plot an lme or nls object
Initialize

Initialize Object
recalc.reStruct

Recalculate for an reStruct Object
nlmeControl

Control Values for nlme Fit
ranef.lmList

Extract lmList Random Effects
logDet.corStruct

Extract corStruct Log-Determinant
gls

Fit Linear Model Using Generalized Least Squares
intervals.lme

Confidence Intervals on lme Parameters
plot.ranef.lme

Plot a ranef.lme Object
varConstPower

Constant Plus Power Variance Function
logDet.pdMat

Extract Log-Determinant from a pdMat Object
logLik.varFunc

Extract varFunc logLik
corARMA

ARMA(p,q) Correlation Structure
lme.groupedData

LME fit from groupedData Object
varWeights

Extract Variance Function Weights
residuals.gnlsStruct

Calculate gnlsStruct Residuals
formula.pdMat

Extract pdMat Formula
reStruct

Random Effects Structure
summary.corStruct

Summarize a corStruct Object
summary.lme

Summarize an lme Object
intervals.lmList

Confidence Intervals on lmList Coefficients
phenoModel

Model function for the Phenobarb data
logLik.gnls

Log-Likelihood of a gnls Object
summary.lmList

Summarize an lmList Object
pdNatural

General Positive-Definite Matrix in Natural Parametrization
predict.lme

Predictions from an lme Object
needUpdate.modelStruct

Check if a modelStruct Object Needs Updating
logDet.reStruct

Extract reStruct Log-Determinants
varPower

Power Variance Function
plot.Variogram

Plot a Variogram Object
pdClasses

Positive-Definite Matrix Classes
lmeStruct

Linear Mixed-Effects Structure
getData

Extract Data from an Object
pairs.lmList

Pairs Plot of an lmList Object
plot.nmGroupedData

Plot an nmGroupedData Object
nlsList.selfStart

nlsList Fit from a selfStart Function
varClasses

Variance Function Classes
pdLogChol

General Positive-Definite Matrix
plot.intervals.lmList

Plot lmList Confidence Intervals
logDet

Extract the Logarithm of the Determinant
Initialize.reStruct

Initialize reStruct Object
print.summary.pdMat

Print a summary.pdMat Object
summary.modelStruct

Summarize a modelStruct Object
plot.nffGroupedData

Plot an nffGroupedData Object
varFixed

Fixed Variance Function
qqnorm.gls

Normal Plot of Residuals from a gls Object
plot.nfnGroupedData

Plot an nfnGroupedData Object
summary.pdMat

Summarize a pdMat Object
residuals.lmList

Extract lmList Residuals
getCovariate.corStruct

Extract corStruct Object Covariate
isInitialized

Check if Object is Initialized
pdConstruct

Construct pdMat Objects
qqnorm.lme

Normal Plot of Residuals or Random Effects from an lme Object
varComb

Combination of Variance Functions
getResponse

Extract Response Variable from an Object
coef.modelStruct

Extract modelStruct Object Coefficients
recalc

Recalculate Condensed Linear Model Object
print.varFunc

Print a varFunc Object
Variogram.corGaus

Calculate Semi-variogram for a corGaus Object
summary.nlsList

Summarize an nlsList Object
summary.varFunc

Summarize varFunc Object
getGroups.lme

Extract lme Object Groups
predict.gnls

Predictions from a gnls Object
as.matrix.corStruct

Matrix of a corStruct Object
pdFactor

Square-Root Factor of a Positive-Definite Matrix
as.matrix.pdMat

Matrix of a pdMat Object
gnlsStruct

Generalized Nonlinear Least Squares Structure
lmeScale

Scale for lme Optimization
varExp

Exponential Variance Function
recalc.modelStruct

Recalculate for a modelStruct Object
residuals.gls

Extract gls Residuals
recalc.corStruct

Recalculate for corStruct Object
update.varFunc

Update varFunc Object
summary.gls

Summarize a gls Object
Variogram.gls

Calculate Semi-variogram for Residuals from a gls Object
update.modelStruct

Update a modelStruct Object
collapse

Collapse According to Groups
nlme

Nonlinear Mixed-Effects Models
varIdent

Constant Variance Function
random.effects

Extract Random Effects
simulate.lme

simulate lme models
coef.lme

Extract lme Coefficients
recalc.varFunc

Recalculate for varFunc Object
solve.pdMat

Calculate Inverse of a Positive-Definite Matrix
fixef.lmList

Extract lmList Fixed Effects
logLik.reStruct

Calculate reStruct Log-Likelihood
logLik.gnlsStruct

Log-Likelihood of a gnlsStruct Object
gnlsObject

Fitted gnls Object
pairs.compareFits

Pairs Plot of compareFits Object
residuals.nlmeStruct

Calculate nlmeStruct Residuals
plot.ACF

Plot an ACF Object
fitted.lmList

Extract lmList Fitted Values
getGroups.data.frame

Extract Groups from a Data Frame
pdConstruct.pdBlocked

Construct pdBlocked Objects
Initialize.glsStruct

Initialize a glsStruct Object
Names.reStruct

Names of an reStruct Object
Dim

Extract Dimensions from an Object
corSpatial

Spatial Correlation Structure
residuals.glsStruct

Calculate glsStruct Residuals
residuals.lmeStruct

Calculate lmeStruct Residuals
varWeights.glsStruct

Variance Weights for glsStruct Object
intervals.gls

Confidence Intervals on gls Parameters
logLik.lmeStruct

Log-Likelihood of an lmeStruct Object
needUpdate

Check if Update is Needed
nlsList

List of nls Objects with a Common Model
plot.gls

Plot a gls Object
plot.augPred

Plot an augPred Object
plot.compareFits

Plot a compareFits Object
splitFormula

Split a Formula
predict.gls

Predictions from a gls Object
varWeights.lmeStruct

Variance Weights for lmeStruct Object
Machines

Productivity Scores for Machines and Workers
Ovary

Counts of Ovarian Follicles
MathAchSchool

School demographic data for MathAchieve
Muscle

Contraction of heart muscle sections
Spruce

Growth of Spruce Trees
Wheat

Yields by growing conditions
Relaxin

Assay for Relaxin
Wheat2

Wheat Yield Trials
Gasoline

Refinery yield of gasoline
Dialyzer

High-Flux Hemodialyzer
Wafer

Modeling of Analog MOS Circuits
PBG

Effect of Phenylbiguanide on Blood Pressure
Earthquake

Earthquake Intensity
Remifentanil

Pharmacokinetics of remifentanil
MathAchieve

Mathematics achievement scores
Assay

Bioassay on Cell Culture Plate
Tetracycline2

Pharmacokinetics of tetracycline
Cefamandole

Pharmacokinetics of Cefamandole
IGF

Radioimmunoassay of IGF-I Protein
Soybean

Growth of soybean plants
BodyWeight

Rat weight over time for different diets
ergoStool

Ergometrics experiment with stool types
Rail

Evaluation of Stress in Railway Rails
Fatigue

Cracks caused by metal fatigue
Glucose2

Glucose Levels Following Alcohol Ingestion
Pixel

X-ray pixel intensities over time
Nitrendipene

Assay of nitrendipene
Gun

Methods for firing naval guns
bdf

Language scores
Tetracycline1

Pharmacokinetics of tetracycline
Oxide

Variability in Semiconductor Manufacturing
Glucose

Glucose levels over time
Alfalfa

Split-Plot Experiment on Varieties of Alfalfa
Meat

Tenderness of meat
RatPupWeight

The weight of rat pups
Quinidine

Quinidine Kinetics
Milk

Protein content of cows' milk
Orthodont

Growth curve data on an orthdontic measurement
Oxboys

Heights of Boys in Oxford
Oats

Split-plot Experiment on Varieties of Oats
Phenobarb

Phenobarbitol Kinetics